MOOC : Viral Hepatitis
- Sciences médicales, Médecine
Informations pratiques sur le MOOC
Description du MOOC
Hepatitis is an acute or chronic inflammation of the liver. Viral hepatitis is most commonly caused by five viruses : A, B, C, D, and E. Some infections will resolve without any serious problems, while others can induce acute liver failure or be chronic and cause fibrosis, cirrhosis, and liver cancer. Globally viral hepatitis results in high mortality worldwide, almost equal to tuberculosis and more than HIV and malaria. Most deaths occur indirectly from liver scarring or liver cancer. Viral hepatitis is considered by WHO a very serious public health issue. In this MOOC, you will find the latest developments on the intimate structure and pathophysiology of hepatic viruses and on the epidemiology and clinical courses of hepatitis which may differ in developed and in low and middle income countries. You will learn about prevention of hepatitis A, B and D by immunization and about the most recent developments of efficient treatments of hepatitis B and hepatitis C which allow to get rid of virus B in 90% of patients and to definitely cure hepatitis C in 95% of them. Clear international guidelines are now available for these treatments.
Despite these progresses, the mortality of viral hepatitis remains high through the world (1.6 million death in 2016 according to WHO) particularly since access to screening, prevention and efficient medications remains critically low in many developping countries, but not only.
At last you will learn about the many public health issues of viral hepatitis and the ambitious plan of WHO to eradicate viral hepatitis by 2030.
This MOOC is organized in 6 chapters of 2 to 9 sessions each. Each session includes a short video and 2 multiple choice questions in english to help you test your understanding. There are 10 to 18 multiple choice questions at the end of each chapter. A certification exam (in English) is accessible only for students registered to the “qualifying path”. The videos are in English, subtitles in English and French are provided.
Plan du MOOC
Chapter 1 : Generalities on viral hepatitis
- W1-1: Generalities on hepatitis viruses
- W1-2: Natural history of viral hepatitis
- W1-3: Evaluation of fibrosis in patients with chronic hepatitis : non invasive tests
- W1-4: Viral hepatocarcinogenesis
- W1-5: Specific features related to populations and continents
- W1-6: Co-infections in patients with viral hepatitis
Chapter 2 : Hepatitis A/Hépatite A
- W2-1 : Hepatitis A virus : pathophysiology, virological diagnosis and follow-up of HAV infection
- W2-2 : Epidemiology and natural history of hepatitis A
Chapter 3 : Hepatitis B and ?
- W3-1: Virology and pathophysiology of hepatitis B virus
- W3-2: Hepatitis B infection virological diagnosis
- W3-3: Epidemiology of viral hepatitis B
- W3-4: Natural history and complications of viral hepatitis B
- W3-5: Hepatitis D virus : pathophysiology and virological diagnosis
- W3-6: Natural history of hepatitis D
- W3-7: Viral hepatitis B in Africa
- W3-8: Treatment of viral hepatitis B and B-D
- W3-9: Vaccination against HBV
Chapter 4 : Hepatitis C
- W4-1: Virology of hepatitis C virus and pathophysiology
- W4-2: Epidemiology of viral hepatitis C
- W4-3: Hepatitis C infection virological diagnosis
- W4-4: Natural history and complications of viral hepatitis C
- W4-5: Peculiarities of hepatitis C in Asia
- W4-6: Treatment of hepatitis C
- W4-7: where are we up to with HCV vaccination ?
Chapter 5 : Hepatitis E and non-alphabetical hepatitis
- W5-1: Hepatitis E virus and pathophysiology of infection by HEV
- W5-2: Epidemiology, natural history, complications and treatment of viral hepatitis E
- W5-3: Differential diagnosis of non alphabetical hepatitis
Chapter 6 : Major issues in viral hepatitis
- W6-1: Viral hepatitis screening
- W6-2: Mother-to-child transmission
- W6-3: Public health issues of hepatitis in developped countries
- W6-4: Management of treated and untreated patients with hepatitis
- W6-5: HBV cure
- W6-6: HCV elimination
- W6-7: Prioritization of the initiatives for the WHO Elimination program
Please note, only the "Qualifying" formula gives the right to a qualifying certification issued by Fun and the Institut Pasteur. In addition, there will be no certificate of successful follow-up, neither for the "Discovery" formula, nor for the "Qualifying" formula.
- Certificat proposé : oui (payant)
- Attestation proposée : non
- Public visé :
This MOOC aims to reach anybody who wishes to learn more about emerging viruses and pandemics, whether scientist, medical doctor or other health workers, staff of governmental and non-governmental agencies or students in life sciences.
- Attendus du MOOC :
We recommend a good scientific background (such as a bachelor of life science).
- Du cours : Licence restrictive
- Du contenu produit par les participants : Licence restrictive