MOOC : Advances in Stem Cell Biology
- Sciences de la vie, Biologie, Biochimie, Ecologie
Informations pratiques sur le MOOC
Description du MOOC
Stem cells have the spectacular ability to restore the function of damaged tissues, providing major opportunities for fundamental studies on organogenesis, regeneration, diseases, and ageing. In spite of intense research in this field, many unanswered questions remain regarding stem cell regulation and function.
The Advances in Stem Cell Biology MOOC was created to provide an overview of stem cell biology, the properties of stem cells and their potential in directing organogenesis and regeneration in different organisms, and how they can be exploited for therapeutic purposes.
This MOOC is organized in 5 chapters of 2 to 10 sessions each. Each session includes a short video and 2 multiple choice questions in english to help you test your understanding. There are 4 to 20 multiple choice questions at the end of each chapter. A certification exam (in English) is accessible only for students registered to the “qualifying path”. The videos are in English, subtitles in English and French are provided.
Plan du MOOC
Chapter 1 – General concepts in stem cell biology
- W1-1: What are Stem cells
- W1-2: What defines the fate of stem cells ?
- W1-3: Introduction to asymmetric cell division
- W1-4: Asymmetric cell division: the cellular and molecular processes
Chapter 2 – Tissue specific stem cells
- W2-1: Intestinal stem cells
- W2-2: Drosophila Intestinal Stem Cells
- W2-3: Introduction to Hematopoietic stem cells
- W2-4: Origins of hematopoietic stem cells
- W2-5: Tracking the journey of hematopoietic stem cells in live zebrafish embryos
- W2-6: Neural Stem cells
- W2-7: Skeletal muscle identity
- W2-8: Skeletal muscle stem cell properties and ageing
- W2-9: Deconstructing and reconstructing a satellite cell niche
- W2-10: Heart regeneration / Régénération cardiaque.
Chapter 3 – Pluripotent stem cells
- W3-1: Human pluripotent stem cell derivation
- W3-2: What are the most common methods to generate iPSCs ?
- W3-3: Specification and segregation of embryonic vs. extra-embryonic stem cells
- W3-4: Differentiation of ICM cells: the underlying mechanisms
- W3-5: Derivation of mouse embryonic stem cells
- W3-6: Derivation of human embryonic stem cells
Chapter 4: Organoids
- W4-1: Using ES cells to understand how cells build organisms
- W4-2: Self-organization of embryonic organoids
Chapter 5: Stem cell applications
- W5-1: Intestinal cancer stem cells
- W5-2: The bioethics of stem cell research and therapy
Please note, only the "Qualifying" formula gives the right to a qualifying certification issued by Fun and the Institut Pasteur. In addition, there will be no certificate of successful follow-up, neither for the "Discovery" formula, nor for the "Qualifying" formula.
- Certificat proposé : oui (payant)
- Attestation proposée : non
- Public visé :
This MOOC aims to reach anybody who wishes to learn more about emerging viruses and pandemics, whether scientist, medical doctor or other health workers, staff of governmental and non-governmental agencies or students in life sciences.
- Attendus du MOOC :
We recommend a good scientific background (such as a bachelor of life science)
During this MOOC you will learn about the characteristics and propertiesof stem cells, along with the latest discoveries in the field from general concepts to different categories of stem cells, and how they participate in organogenesis in the organism - and in vitro.
- Du cours : Licence restrictive
- Du contenu produit par les participants : Licence restrictive
Suivez le MOOC sur les réseaux sociaux
Prof. Shahragim Tajbakhsh – Stem Cells and Development team at Institut Pasteur
Vania Rosas Magallanes
Project officer of the LaBex REVIVE
With the participation of
- Shahragim Tajbakhsh (Institut Pasteur, France)
- François Schweisguth (Institut Pasteur, France)
- Marc Van de Wetering (Princess Maxima Center for Pediatric Oncology, Netherlands)
- Allison Bardin (Institut Curie, France)
- Ana Cumano (Institut Pasteur, France)
- Philippe Herbomel (Institut Pasteur, France)
- Pierre-Marie Lledo (Institut Pasteur, France)
- Matthias Lutolf (EPFL, Switzerland)
- Sigolène Meilhac (Institut Pasteur, Institut Imagine, France)
- Laurence Daheron (Harvard Stem Cell Institute, USA)
- Kat Hadjantonakis (Sloan Kettering Institute, USA)
- Jenny Nichols (Cambridge Stem Cell Institute, UK)
- Alfonso Martinez Arias (University of Cambridge, UK)
- Emmanuelle Rial-Sebbag (Inserm, France)